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Insight into the mechanism of DNA synthesis by human terminal deoxynucleotidyltransferase

Terminal deoxynucleotidyltransferase (TdT) is a member of the DNA polymerase X family that is responsible for random addition of nucleotides to single-stranded DNA. We present investigation into the role of metal ions and specific interactions of dNTP with active-site amino acid residues in the mech...

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Detalles Bibliográficos
Autores principales:	Kuznetsova, Aleksandra A, Tyugashev, Timofey E, Alekseeva, Irina V, Timofeyeva, Nadezhda A, Fedorova, Olga S, Kuznetsov, Nikita A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348634/ https://www.ncbi.nlm.nih.gov/pubmed/35914812 http://dx.doi.org/10.26508/lsa.202201428

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