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Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa

Canonical aminoglycosides are a large group of antibiotics, where the part of chemical diversity stems from the substitution of the neamine ring system on positions 5 and 6. Certain aminoglycoside modifying enzymes can modify a broad range of 4,5- and 4,6-disubstituted aminoglycosides, with some as...

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Detalles Bibliográficos
Autores principales: Zieliński, Michał, Blanchet, Jonathan, Hailemariam, Sophia, Berghuis, Albert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348671/
https://www.ncbi.nlm.nih.gov/pubmed/35921328
http://dx.doi.org/10.1371/journal.pone.0269684