Cargando…

Measuring quality of DNA sequence data via degradation

We formulate and apply a novel paradigm for characterization of genome data quality, which quantifies the effects of intentional degradation of quality. The rationale is that the higher the initial quality, the more fragile the genome and the greater the effects of degradation. We demonstrate that t...

Descripción completa

Detalles Bibliográficos
Autores principales: Karr, Alan F., Hauzel, Jason, Porter, Adam A., Schaefer, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348684/
https://www.ncbi.nlm.nih.gov/pubmed/35921272
http://dx.doi.org/10.1371/journal.pone.0271970