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Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets

Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D). Nevertheless, circadian regulation of lipid metabolism in human pancreatic islets has not been explor...

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Detalles Bibliográficos
Autores principales: Petrenko, Volodymyr, Sinturel, Flore, Loizides-Mangold, Ursula, Montoya, Jonathan Paz, Chera, Simona, Riezman, Howard, Dibner, Charna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348689/
https://www.ncbi.nlm.nih.gov/pubmed/35921354
http://dx.doi.org/10.1371/journal.pbio.3001725