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Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer

Introduction: DNA damage and resulting neoantigen formation is considered a mechanism for synergy between radiotherapy and PD-1/PD-L1 pathway inhibition to induce antitumor immune response. We investigated neoadjuvant chemoradiotherapy (nCRT)-induced changes in CD8+ tumor infiltrating lymphocyte, PD...

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Detalles Bibliográficos
Autores principales:	Baretti, Marina, Zhu, Qingfeng, Fu, Wei, Meyer, Jeffrey, Wang, Hao, Anders, Robert A., Azad, Nilofer S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348692/ https://www.ncbi.nlm.nih.gov/pubmed/35937503 http://dx.doi.org/10.18632/oncotarget.28255

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