Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer

Proper Hedgehog (HH) signaling is essential for embryonic development, while aberrant HH signaling drives pediatric and adult cancers. HH signaling is frequently dysregulated in pancreatic cancer, yet its role remains controversial, with both tumor-promoting and tumor-restraining functions reported....

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Detalles Bibliográficos
Autores principales: Scales, Michael K., Velez-Delgado, Ashley, Steele, Nina G., Schrader, Hannah E., Stabnick, Anna M., Yan, Wei, Mercado Soto, Nayanna M., Nwosu, Zeribe C., Johnson, Craig, Zhang, Yaqing, Salas-Escabillas, Daniel J., Menjivar, Rosa E., Maurer, H. Carlo, Crawford, Howard C., Bednar, Filip, Olive, Kenneth P., Pasca di Magliano, Marina, Allen, Benjamin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348714/
https://www.ncbi.nlm.nih.gov/pubmed/35867772
http://dx.doi.org/10.1371/journal.pgen.1010315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348714/
https://www.ncbi.nlm.nih.gov/pubmed/35867772
http://dx.doi.org/10.1371/journal.pgen.1010315

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