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Estimation of causal effects of a time-varying exposure at multiple time points through multivariable mendelian randomization

Mendelian Randomisation (MR) is a powerful tool in epidemiology that can be used to estimate the causal effect of an exposure on an outcome in the presence of unobserved confounding, by utilising genetic variants as instrumental variables (IVs) for the exposure. The effect estimates obtained from MR...

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Detalles Bibliográficos
Autores principales: Sanderson, Eleanor, Richardson, Tom G., Morris, Tim T., Tilling, Kate, Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348730/
https://www.ncbi.nlm.nih.gov/pubmed/35849575
http://dx.doi.org/10.1371/journal.pgen.1010290