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Estimation of causal effects of a time-varying exposure at multiple time points through multivariable mendelian randomization
Mendelian Randomisation (MR) is a powerful tool in epidemiology that can be used to estimate the causal effect of an exposure on an outcome in the presence of unobserved confounding, by utilising genetic variants as instrumental variables (IVs) for the exposure. The effect estimates obtained from MR...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348730/ https://www.ncbi.nlm.nih.gov/pubmed/35849575 http://dx.doi.org/10.1371/journal.pgen.1010290 |