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Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer

The epithelial-to-mesenchymal transition (EMT) is frequently co-opted by cancer cells to enhance migratory and invasive cell traits. It is a key contributor to heterogeneity, chemoresistance, and metastasis in many carcinoma types, where the intermediate EMT state plays a critical tumor-initiating r...

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Detalles Bibliográficos
Autores principales: Brown, Meredith S., Abdollahi, Behnaz, Wilkins, Owen M., Lu, Hanxu, Chakraborty, Priyanka, Ognjenovic, Nevena B., Muller, Kristen E., Jolly, Mohit Kumar, Christensen, Brock C., Hassanpour, Saeed, Pattabiraman, Diwakar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348802/
https://www.ncbi.nlm.nih.gov/pubmed/35921406
http://dx.doi.org/10.1126/sciadv.abj8002