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Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer
The epithelial-to-mesenchymal transition (EMT) is frequently co-opted by cancer cells to enhance migratory and invasive cell traits. It is a key contributor to heterogeneity, chemoresistance, and metastasis in many carcinoma types, where the intermediate EMT state plays a critical tumor-initiating r...
Autores principales: | Brown, Meredith S., Abdollahi, Behnaz, Wilkins, Owen M., Lu, Hanxu, Chakraborty, Priyanka, Ognjenovic, Nevena B., Muller, Kristen E., Jolly, Mohit Kumar, Christensen, Brock C., Hassanpour, Saeed, Pattabiraman, Diwakar R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348802/ https://www.ncbi.nlm.nih.gov/pubmed/35921406 http://dx.doi.org/10.1126/sciadv.abj8002 |
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