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Robust and Efficient Assessment of Potency (REAP) as a quantitative tool for dose-response curve estimation
The median-effect equation has been widely used to describe the dose-response relationship and identify compounds that activate or inhibit specific disease targets in contemporary drug discovery. However, the experimental data often contain extreme responses, which may significantly impair the estim...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348845/ https://www.ncbi.nlm.nih.gov/pubmed/35921131 http://dx.doi.org/10.7554/eLife.78634 |