Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels

Otopetrin (OTOP) channels are proton-selective ion channels conserved among vertebrates and invertebrates, with no structural similarity to other ion channels. There are three vertebrate OTOP channels (OTOP1, OTOP2, and OTOP3), of which one (OTOP1) functions as a sour taste receptor. Whether extrace...

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Detalles Bibliográficos
Autores principales: Teng, Bochuan, Kaplan, Joshua P, Liang, Ziyu, Krieger, Zachary, Tu, Yu-Hsiang, Burendei, Batuujin, Ward, Andrew B, Liman, Emily R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348849/
https://www.ncbi.nlm.nih.gov/pubmed/35920807
http://dx.doi.org/10.7554/eLife.77946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348849/
https://www.ncbi.nlm.nih.gov/pubmed/35920807
http://dx.doi.org/10.7554/eLife.77946

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