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Deconstructing cold-induced brown adipocyte neogenesis in mice

Cold exposure triggers neogenesis in classic interscapular brown adipose tissue (iBAT) that involves activation of β1-adrenergic receptors, proliferation of PDGFRA+ adipose tissue stromal cells (ASCs), and recruitment of immune cells whose phenotypes are presently unknown. Single-cell RNA-sequencing...

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Detalles Bibliográficos
Autores principales: Burl, Rayanne B, Rondini, Elizabeth Ann, Wei, Hongguang, Pique-Regi, Roger, Granneman, James G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348851/
https://www.ncbi.nlm.nih.gov/pubmed/35848799
http://dx.doi.org/10.7554/eLife.80167