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Towards a unified model of naive T cell dynamics across the lifespan

Naive CD4 and CD8 T cells are cornerstones of adaptive immunity, but the dynamics of their establishment early in life and how their kinetics change as they mature following release from the thymus are poorly understood. Further, due to the diverse signals implicated in naive T cell survival, it has...

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Detalles Bibliográficos
Autores principales: Rane, Sanket, Hogan, Thea, Lee, Edward, Seddon, Benedict, Yates, Andrew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348855/
https://www.ncbi.nlm.nih.gov/pubmed/35678373
http://dx.doi.org/10.7554/eLife.78168