Integrative genome modeling platform reveals essentiality of rare contact events in 3D genome organizations

A multitude of sequencing-based and microscopy technologies provide the means to unravel the relationship between the three-dimensional organization of genomes and key regulatory processes of genome function. Here, we develop a multimodal data integration approach to produce populations of single-ce...

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Detalles Bibliográficos
Autores principales: Boninsegna, Lorenzo, Yildirim, Asli, Polles, Guido, Zhan, Yuxiang, Quinodoz, Sofia A., Finn, Elizabeth H., Guttman, Mitchell, Zhou, Xianghong Jasmine, Alber, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349046/
https://www.ncbi.nlm.nih.gov/pubmed/35817938
http://dx.doi.org/10.1038/s41592-022-01527-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349046/
https://www.ncbi.nlm.nih.gov/pubmed/35817938
http://dx.doi.org/10.1038/s41592-022-01527-x

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