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Integrative genome modeling platform reveals essentiality of rare contact events in 3D genome organizations
A multitude of sequencing-based and microscopy technologies provide the means to unravel the relationship between the three-dimensional organization of genomes and key regulatory processes of genome function. Here, we develop a multimodal data integration approach to produce populations of single-ce...
Autores principales: | Boninsegna, Lorenzo, Yildirim, Asli, Polles, Guido, Zhan, Yuxiang, Quinodoz, Sofia A., Finn, Elizabeth H., Guttman, Mitchell, Zhou, Xianghong Jasmine, Alber, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349046/ https://www.ncbi.nlm.nih.gov/pubmed/35817938 http://dx.doi.org/10.1038/s41592-022-01527-x |
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