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Expression of decitabine-targeted oncogenes in meningiomas in vivo

Treatment of meningiomas refractory to surgery and irradiation is challenging and effective chemotherapies are still lacking. Recently, in vitro analyses revealed decitabine (DCT, 5-aza-2’–deoxycytidine) to be effective in high-grade meningiomas and, moreover, to induce hypomethylation of distinct o...

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Detalles Bibliográficos
Autores principales: Canisius, Julian, Wagner, Andrea, Bunk, Eva Christina, Spille, Dorothee Cäcilia, Stögbauer, Louise, Grauer, Oliver, Hess, Katharina, Thomas, Christian, Paulus, Werner, Stummer, Walter, Senner, Volker, Brokinkel, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349086/
https://www.ncbi.nlm.nih.gov/pubmed/35445910
http://dx.doi.org/10.1007/s10143-022-01789-1