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Positron Emission Tomography reveals age-associated hypothalamic microglial activation in women

In rodents, hypothalamic inflammation plays a critical role in aging and age-related diseases. Hypothalamic inflammation has not previously been assessed in vivo in humans. We used Positron Emission Tomography (PET) with a radiotracer sensitive to the translocator protein (TSPO) expressed by activat...

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Detalles Bibliográficos
Autores principales: Butler, Tracy, Glodzik, Lidia, Wang, Xiuyuan Hugh, Xi, Ke, Li, Yi, Pan, Hong, Zhou, Liangdong, Chiang, Gloria Chia-Yi, Morim, Simon, Wickramasuriya, Nimmi, Tanzi, Emily, Maloney, Thomas, Harvey, Patrick, Mao, Xiangling, Razlighi, Qolamreza Ray, Rusinek, Henry, Shungu, Dikoma C., de Leon, Mony, Atwood, Craig S., Mozley, P. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349172/
https://www.ncbi.nlm.nih.gov/pubmed/35922659
http://dx.doi.org/10.1038/s41598-022-17315-8