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Positron Emission Tomography reveals age-associated hypothalamic microglial activation in women
In rodents, hypothalamic inflammation plays a critical role in aging and age-related diseases. Hypothalamic inflammation has not previously been assessed in vivo in humans. We used Positron Emission Tomography (PET) with a radiotracer sensitive to the translocator protein (TSPO) expressed by activat...
Autores principales: | Butler, Tracy, Glodzik, Lidia, Wang, Xiuyuan Hugh, Xi, Ke, Li, Yi, Pan, Hong, Zhou, Liangdong, Chiang, Gloria Chia-Yi, Morim, Simon, Wickramasuriya, Nimmi, Tanzi, Emily, Maloney, Thomas, Harvey, Patrick, Mao, Xiangling, Razlighi, Qolamreza Ray, Rusinek, Henry, Shungu, Dikoma C., de Leon, Mony, Atwood, Craig S., Mozley, P. David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349172/ https://www.ncbi.nlm.nih.gov/pubmed/35922659 http://dx.doi.org/10.1038/s41598-022-17315-8 |
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