Histone H3K36me2 and H3K36me3 form a chromatin platform essential for DNMT3A-dependent DNA methylation in mouse oocytes

Establishment of the DNA methylation landscape of mammalian oocytes, mediated by the DNMT3A-DNMT3L complex, is crucial for reproduction and development. In mouse oocytes, high levels of DNA methylation occur exclusively in the transcriptionally active regions, with moderate to low levels of methylat...

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Detalles Bibliográficos
Autores principales: Yano, Seiichi, Ishiuchi, Takashi, Abe, Shusaku, Namekawa, Satoshi H., Huang, Gang, Ogawa, Yoshihiro, Sasaki, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349174/
https://www.ncbi.nlm.nih.gov/pubmed/35922445
http://dx.doi.org/10.1038/s41467-022-32141-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349174/
https://www.ncbi.nlm.nih.gov/pubmed/35922445
http://dx.doi.org/10.1038/s41467-022-32141-2

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