Extracellular vesicles derived from GMSCs stimulated with TNF-α and IFN-α promote M2 macrophage polarization via enhanced CD73 and CD5L expression

Immunoregulatory properties of mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) are promising. Gingival tissue-derived MSCs (GMSCs) have unique immunoregulatory capacity and secrete large amounts of EVs. Recent findings suggest that priming MSCs with inflammatory stimuli is an effect...

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Detalles Bibliográficos
Autores principales: Watanabe, Yukari, Fukuda, Takao, Hayashi, Chikako, Nakao, Yuki, Toyoda, Masaaki, Kawakami, Kentaro, Shinjo, Takanori, Iwashita, Misaki, Yamato, Hiroaki, Yotsumoto, Karen, Taketomi, Takaharu, Uchiumi, Takeshi, Sanui, Terukazu, Nishimura, Fusanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349189/
https://www.ncbi.nlm.nih.gov/pubmed/35922474
http://dx.doi.org/10.1038/s41598-022-17692-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349189/
https://www.ncbi.nlm.nih.gov/pubmed/35922474
http://dx.doi.org/10.1038/s41598-022-17692-0

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