Cargando…

Extracellular vesicles derived from GMSCs stimulated with TNF-α and IFN-α promote M2 macrophage polarization via enhanced CD73 and CD5L expression

Immunoregulatory properties of mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) are promising. Gingival tissue-derived MSCs (GMSCs) have unique immunoregulatory capacity and secrete large amounts of EVs. Recent findings suggest that priming MSCs with inflammatory stimuli is an effect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watanabe, Yukari, Fukuda, Takao, Hayashi, Chikako, Nakao, Yuki, Toyoda, Masaaki, Kawakami, Kentaro, Shinjo, Takanori, Iwashita, Misaki, Yamato, Hiroaki, Yotsumoto, Karen, Taketomi, Takaharu, Uchiumi, Takeshi, Sanui, Terukazu, Nishimura, Fusanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349189/ https://www.ncbi.nlm.nih.gov/pubmed/35922474 http://dx.doi.org/10.1038/s41598-022-17692-0

Ejemplares similares

miR-1260b inhibits periodontal bone loss by targeting ATF6β mediated regulation of ER stress
por: Hayashi, Chikako, et al.
Publicado: (2022)

Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages
por: Yotsumoto, Karen, et al.
Publicado: (2020)

Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss
por: Nakao, Yuki, et al.
Publicado: (2020)

Identification of Novel Amelogenin-Binding Proteins by Proteomics Analysis
por: Fukuda, Takao, et al.
Publicado: (2013)

Inhibition of Sprouty2 polarizes macrophages toward an M2 phenotype by stimulation with interferon γ and Porphyromonas gingivalis lipopolysaccharide
por: Atomura, Ryo, et al.
Publicado: (2016)

XAF1 overexpression exacerbates diabetes by promoting pancreatic β-cell apoptosis
por: Nishimura, Yuki, et al.
Publicado: (2022)

Adipose-specific C-C motif chemokine ligand (CCL) 19 overexpression drives the mice to both insulin resistance and weight gain
por: Hayashi, Masato, et al.
Publicado: (2021)

Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure
por: Sano, Tomomi, et al.
Publicado: (2019)

SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth
por: Alshargabi, Rehab, et al.
Publicado: (2020)

CD39 Produced from Human GMSCs Regulates the Balance of Osteoclasts and Osteoblasts through the Wnt/β-Catenin Pathway in Osteoporosis
por: Wu, Wenbin, et al.
Publicado: (2020)

The Roles of CD73 in Cancer
por: Gao, Zhao-wei, et al.
Publicado: (2014)

Antibiotic effects against periodontal bacteria in organ cultured tissue
por: Takeshita, Masaaki, et al.
Publicado: (2016)

The Clinical Significance of CD73 in Cancer
por: Bach, Niklas, et al.
Publicado: (2023)

Defining the CD39/CD73 Axis in SARS-CoV-2 Infection: The CD73(-) Phenotype Identifies Polyfunctional Cytotoxic Lymphocytes
por: Ahmadi, Parimah, et al.
Publicado: (2020)

A Case Report of Improved Palmoplantar Pustulosis following Periodontal Treatment and Possible Association with Diminished Systemic Subclinical Inflammation
por: Yamashita, Akiko, et al.
Publicado: (2021)

Bispecific antibody CD73xEGFR more selectively inhibits the CD73/adenosine immune checkpoint on cancer cells and concurrently counteracts pro-oncogenic activities of CD73 and EGFR
por: Ploeg, Emily Maria, et al.
Publicado: (2023)

CD73 is involved in lymphocyte binding to the endothelium: characterization of lymphocyte-vascular adhesion protein 2 identifies it as CD73
Publicado: (1995)

High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice
por: Shinjo, Takanori, et al.
Publicado: (2015)

CD28 engagement inhibits CD73-mediated regulatory activity of CD8(+) T cells
por: Lai, Yo-Ping, et al.
Publicado: (2021)

CD73 is associated with poor prognosis in HNSCC
por: Ren, Zhen-Hu, et al.
Publicado: (2016)

CD73 Promotes Chronic Lymphocytic Leukemia
por: Allard, David, et al.
Publicado: (2022)

CD73: Friend or Foe in Lung Injury
por: Hu, Xiu-Min, et al.
Publicado: (2023)

Glucocorticoids inhibit type I IFN beta signaling and the upregulation of CD73 in human lung
por: Jalkanen, Juho, et al.
Publicado: (2020)

Low expression of CD39 and CD73 genes in centenarians compared with octogenarians
por: Crooke, Almudena, et al.
Publicado: (2017)

Monitoring and characterizing soluble and membrane-bound ectonucleotidases CD73 and CD39
por: Goueli, Said A., et al.
Publicado: (2019)

CD39 and CD73 as Promising Therapeutic Targets: What Could Be the Limitations?
por: Battastini, Ana Maria Oliveira, et al.
Publicado: (2021)

Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells
por: Rosemblatt, Mariana V., et al.
Publicado: (2021)

CD39/CD73/A2AR pathway and cancer immunotherapy
por: Xia, Chenglai, et al.
Publicado: (2023)

The ectonucleotidases CD39 and CD73 on T cells: The new pillar of hematological malignancy
por: Jiang, Xuan, et al.
Publicado: (2023)

Exploring CD39 and CD73 Expression as Potential Biomarkers in Prostate Cancer
por: Gardani, Carla Fernanda Furtado, et al.
Publicado: (2023)

In Vitro Induction of Regulatory CD4(+)CD8α(+) T Cells by TGF-β, IL-7 and IFN-γ
por: Van Kaer, Luc, et al.
Publicado: (2013)

Distinct and Overlapping Effector Functions of Expanded Human CD4(+), CD8α(+) and CD4(-)CD8α(-) Invariant Natural Killer T Cells
por: O'Reilly, Vincent, et al.
Publicado: (2011)

Analysis of cell-biomaterial interaction through cellular bridge formation in the interface between hGMSCs and CaP bioceramics
por: Benjumeda Wijnhoven, Isabel, et al.
Publicado: (2020)

The Ecto-5’-Nucleotidase/CD73 Inhibitor, α,β-Methylene Adenosine 5’-Diphosphate, Exacerbates Carrageenan-Induced Pleurisy in Rat
por: Caiazzo, Elisabetta, et al.
Publicado: (2019)

Development of Cd8α/α and Cd8α/β T Cells in Major Histocompatibility Complex Class I–Deficient Mice
por: Das, Gobardhan, et al.
Publicado: (1999)

Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice
por: Iwashita, Misaki, et al.
Publicado: (2013)

High Expression of Ecto-Nucleotidases CD39 and CD73 in Human Endometrial Tumors
por: Aliagas, Elisabet, et al.
Publicado: (2014)

The Role of Ectonucleotidases CD39 and CD73 and Adenosine Signaling in Solid Organ Transplantation
por: Roberts, Veena, et al.
Publicado: (2014)

Physiological roles for ecto-5’-nucleotidase (CD73)
por: Colgan, Sean P., et al.
Publicado: (2006)

Host CD73 impairs anti-tumor immunity
por: Salmi, Marko, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_jhotmeatoeus69167rcq8l8ocm