Peptidic defective interfering gene nanoparticles against Omicron, Delta SARS-CoV-2 variants and influenza A virus in vivo

Defective interfering genes (DIGs) are short viral genomes and interfere with wild-type viral replication. Here, we demonstrate that the new designed SARS-CoV-2 DIG (CD3600) can significantly inhibit the replication of SARS-CoV-2 including Alpha, Delta, Kappa and Omicron variants in human HK-2 cells...

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Detalles Bibliográficos
Autores principales: Zhao, Hanjun, Zhang, Chuyuan, Lam, Hoiyan, Meng, Xinjie, Peng, Zheng, Yeung, Man Lung, Chan, Jasper Fuk-Woo, Kai-Wang To, Kelvin, Yuen, Kwok-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349215/
https://www.ncbi.nlm.nih.gov/pubmed/35922403
http://dx.doi.org/10.1038/s41392-022-01138-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349215/
https://www.ncbi.nlm.nih.gov/pubmed/35922403
http://dx.doi.org/10.1038/s41392-022-01138-0

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