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ADAR3 activates NF-κB signaling and promotes glioblastoma cell resistance to temozolomide

The RNA binding protein ADAR3 is expressed exclusively in the brain and reported to have elevated expression in tumors of patients suffering from glioblastoma compared to adjacent brain tissue. Yet, other studies have indicated that glioblastoma tumors exhibit hemizygous deletions of the genomic reg...

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Detalles Bibliográficos
Autores principales: Raghava Kurup, Reshma, Oakes, Eimile K., Vadlamani, Pranathi, Nwosu, Obi, Danthi, Pranav, Hundley, Heather A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349284/
https://www.ncbi.nlm.nih.gov/pubmed/35922651
http://dx.doi.org/10.1038/s41598-022-17559-4