In mouse chronic pancreatitis CD25(+)FOXP3(+) regulatory T cells control pancreatic fibrosis by suppression of the type 2 immune response

Chronic pancreatitis (CP) is characterized by chronic inflammation and the progressive fibrotic replacement of exocrine and endocrine pancreatic tissue. We identify Treg cells as central regulators of the fibroinflammatory reaction by a selective depletion of FOXP3-positive cells in a transgenic mou...

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Detalles Bibliográficos
Autores principales: Glaubitz, Juliane, Wilden, Anika, Golchert, Janine, Homuth, Georg, Völker, Uwe, Bröker, Barbara M., Thiele, Thomas, Lerch, Markus M., Mayerle, Julia, Aghdassi, Ali A., Weiss, Frank U., Sendler, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349313/
https://www.ncbi.nlm.nih.gov/pubmed/35922425
http://dx.doi.org/10.1038/s41467-022-32195-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349313/
https://www.ncbi.nlm.nih.gov/pubmed/35922425
http://dx.doi.org/10.1038/s41467-022-32195-2

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