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Targeting SARS-CoV-2 endoribonuclease: a structure-based virtual screening supported by in vitro analysis

Researchers are focused on discovering compounds that can interfere with the COVID-19 life cycle. One of the important non-structural proteins is endoribonuclease since it is responsible for processing viral RNA to evade detection of the host defense system. This work investigates a hierarchical str...

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Detalles Bibliográficos
Autores principales: Ibrahim, Ibrahim M., Elfiky, Abdo A., Fathy, Mohamed M., Mahmoud, Sara H., ElHefnawi, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349323/
https://www.ncbi.nlm.nih.gov/pubmed/35922447
http://dx.doi.org/10.1038/s41598-022-17573-6