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Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS‐CoV‐2 mRNA vaccination

Durable cell‐mediated immune responses require efficient innate immune signaling and the release of pro‐inflammatory cytokines. How precisely mRNA vaccines trigger innate immune cells for shaping antigen specific adaptive immunity remains unknown. Here, we show that SARS‐CoV‐2 mRNA vaccination prime...

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Detalles Bibliográficos
Autores principales: Theobald, Sebastian J, Simonis, Alexander, Mudler, Julie M, Göbel, Ulrike, Acton, Richard, Kohlhas, Viktoria, Albert, Marie‐Christine, Hellmann, Anna‐Maria, Malin, Jakob J, Winter, Sandra, Hallek, Michael, Walczak, Henning, Nguyen, Phuong‐Hien, Koch, Manuel, Rybniker, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349614/
https://www.ncbi.nlm.nih.gov/pubmed/35785445
http://dx.doi.org/10.15252/emmm.202215888