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mRNA Vaccines Against SARS‐CoV‐2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids

SARS‐CoV‐2 variants are now still challenging all the approved vaccines, including mRNA vaccines. There is an urgent need to develop new generation mRNA vaccines with more powerful efficacy and better safety against SARS‐CoV‐2 variants. In this study, a new set of ionizable lipids named 4N4T are con...

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Detalles Bibliográficos
Autores principales: Chen, Kepan, Fan, Na, Huang, Hai, Jiang, Xin, Qin, Shugang, Xiao, Wen, Zheng, Qian, Zhang, Yupei, Duan, Xing, Qin, Zeyi, Liu, Yongmei, Zeng, Jun, Wei, Yuquan, Song, Xiangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349794/
https://www.ncbi.nlm.nih.gov/pubmed/35942272
http://dx.doi.org/10.1002/adfm.202204692