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Mitotic Activity in Gastrointestinal Stromal Tumors: Can we use Phosphohistone H3 Immunohistochemistry Instead of Hematoxylin and Eosin for Mitotic Count?

OBJECTIVES: In gastrointestinal stromal tumors (GIST), malignancy potential is determined by the prognostic disease risk stratification based on mitosis, tumor size, and location. Phosphohistone H3 (PHH3) is an immunohistochemical marker showing mitotic activity in cells. In this study, we aimed to...

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Detalles Bibliográficos
Autores principales: Erhan, Selma Sengiz, Sensu, Sibel, Keser, Sevinc Hallac, Kangal, Elis, Gul, Aylin Ege, Gundogan, Gokcen Alinak, Sakin, Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Med Bull Sisli Etfal Hosp 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350061/
https://www.ncbi.nlm.nih.gov/pubmed/35990307
http://dx.doi.org/10.14744/SEMB.2021.32798