Synthetic α‐Helical Peptides as Potential Inhibitors of the ACE2 SARS‐CoV‐2 Interaction

During viral cell entry, the spike protein of SARS‐CoV‐2 binds to the α1‐helix motif of human angiotensin‐converting enzyme 2 (ACE2). Thus, alpha‐helical peptides mimicking this motif may serve as inhibitors of viral cell entry. For this purpose, we employed the rigidified diproline‐derived module P...

Descripción completa

Detalles Bibliográficos
Autores principales: Engelhardt, Pascal M., Florez‐Rueda, Sebastián, Drexelius, Marco, Neudörfl, Jörg‐Martin, Lauster, Daniel, Hackenberger, Christian P. R., Kühne, Ronald, Neundorf, Ines, Schmalz, Hans‐Günther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350387/
https://www.ncbi.nlm.nih.gov/pubmed/35785462
http://dx.doi.org/10.1002/cbic.202200372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350387/
https://www.ncbi.nlm.nih.gov/pubmed/35785462
http://dx.doi.org/10.1002/cbic.202200372

Ejemplares similares