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Synthetic α‐Helical Peptides as Potential Inhibitors of the ACE2 SARS‐CoV‐2 Interaction

During viral cell entry, the spike protein of SARS‐CoV‐2 binds to the α1‐helix motif of human angiotensin‐converting enzyme 2 (ACE2). Thus, alpha‐helical peptides mimicking this motif may serve as inhibitors of viral cell entry. For this purpose, we employed the rigidified diproline‐derived module P...

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Detalles Bibliográficos
Autores principales:	Engelhardt, Pascal M., Florez‐Rueda, Sebastián, Drexelius, Marco, Neudörfl, Jörg‐Martin, Lauster, Daniel, Hackenberger, Christian P. R., Kühne, Ronald, Neundorf, Ines, Schmalz, Hans‐Günther
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350387/ https://www.ncbi.nlm.nih.gov/pubmed/35785462 http://dx.doi.org/10.1002/cbic.202200372

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