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Iridium-catalyzed α-selective deuteration of alcohols

The development of chemoselective C(sp(3))-H deuteration is of particular interest in synthetic chemistry. We herein report the α-selective, iridium(iii)-bipyridonate-catalyzed hydrogen(H)/deuterium(D) isotope exchange of alcohols using deuterium oxide (D(2)O) as the primary deuterium source. This m...

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Detalles Bibliográficos
Autores principales:	Itoga, Moeko, Yamanishi, Masako, Udagawa, Taro, Kobayashi, Ayane, Maekawa, Keiko, Takemoto, Yoshiji, Naka, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350590/ https://www.ncbi.nlm.nih.gov/pubmed/35975159 http://dx.doi.org/10.1039/d2sc01805e

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