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Asymmetric synthesis of chromanone lactones via vinylogous conjugate addition of butenolide to 2-ester chromones
Chiral chromanone lactones are a class of natural products with important biological activity. We report a direct diastereo- and enantioselective vinylogous conjugate addition of butenolide to 2-ester substituted chromones. The transformation proceeded well in the presence of as low as 1 mol% of a c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350614/ https://www.ncbi.nlm.nih.gov/pubmed/35975160 http://dx.doi.org/10.1039/d2sc02541h |