miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc

BACKGROUND: Cancer stem cells (CSCs) have been implicated in tumorigenesis and tumor recurrence and metastasis are key therapeutic targets in cancer treatment. MicroRNAs display therapeutic potential by controlling the properties of CSCs; however, whether an association exists between miR-3682-3p an...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Yang, Si-Bo, Zhang, Ye-Wei, Han, Si-Yuan, Jia, Lei, Li, Bo, Zhang, Yi, Zuo, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350627/
https://www.ncbi.nlm.nih.gov/pubmed/36157524
http://dx.doi.org/10.4252/wjsc.v14.i7.539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350627/
https://www.ncbi.nlm.nih.gov/pubmed/36157524
http://dx.doi.org/10.4252/wjsc.v14.i7.539

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