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miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc
BACKGROUND: Cancer stem cells (CSCs) have been implicated in tumorigenesis and tumor recurrence and metastasis are key therapeutic targets in cancer treatment. MicroRNAs display therapeutic potential by controlling the properties of CSCs; however, whether an association exists between miR-3682-3p an...
Autores principales: | Chen, Qian, Yang, Si-Bo, Zhang, Ye-Wei, Han, Si-Yuan, Jia, Lei, Li, Bo, Zhang, Yi, Zuo, Shi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350627/ https://www.ncbi.nlm.nih.gov/pubmed/36157524 http://dx.doi.org/10.4252/wjsc.v14.i7.539 |
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