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Variations on a theme: crystal forms of the amino-acid transporter MhsT

The bacterial amino-acid transporter MhsT from the SLC6A family has been crystallized in complex with different substrates in order to understand the determinants of the substrate specificity of the transporter. Surprisingly, crystals of the different MhsT–substrate complexes showed interrelated but...

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Detalles Bibliográficos
Autores principales: Neumann, Caroline, Focht, Dorota, Trampari, Sofia, Lyons, Joseph A., Nissen, Poul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350835/
https://www.ncbi.nlm.nih.gov/pubmed/35924597
http://dx.doi.org/10.1107/S2053230X22007154