Synthesis of Novel Phthalazinedione-Based Derivatives with Promising Cytotoxic, Anti-bacterial, and Molecular Docking Studies as VEGFR2 Inhibitors

[Image: see text] The parent ester methyl-3-[2-(4-oxo-3-phenyl-3,4-dihydro-phthalazin-1-yloxy)-acetylamino] has 18 compounds. The starting material for alkanoates, their corresponding hydrazides, hydrazones, and dipeptides were produced by chemoselective O-alkylation of 2-phenyl-2,3-dihydrophthalazi...

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Detalles Bibliográficos
Autores principales: El Rayes, Samir M., El Enany, Gaber, Ali, Ibrahim A. I., Ibrahim, Wessam, Nafie, Mohamed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350887/
https://www.ncbi.nlm.nih.gov/pubmed/35936456
http://dx.doi.org/10.1021/acsomega.2c03182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350887/
https://www.ncbi.nlm.nih.gov/pubmed/35936456
http://dx.doi.org/10.1021/acsomega.2c03182

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