Administration of 4-hexylresorcinol increases p53-mediated transcriptional activity in oral cancer cells with the p53 mutation

The p53 mutation is inherent in over 50% of human cancers. In head and neck squamous cell carcinoma, the p53 mutation is associated with a poor prognosis. 4-Hexylresorcinol (4HR) is a pharmacologic chaperone. The present study aimed to investigate the effect of 4HR on p53 transcriptional activity in...

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Detalles Bibliográficos
Autores principales: Kang, Yei-Jin, Yang, Won-Geun, Chae, Weon-Sik, Kim, Dae-Won, Kim, Seong-Gon, Rotaru, Horatiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350967/
https://www.ncbi.nlm.nih.gov/pubmed/35856441
http://dx.doi.org/10.3892/or.2022.8375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350967/
https://www.ncbi.nlm.nih.gov/pubmed/35856441
http://dx.doi.org/10.3892/or.2022.8375

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