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Combining TMZ and SB225002 induces changes of CXCR2 and VEGFR signalling in primary human endothelial cells in vitro

Standard of care therapy for glioblastoma (GBM) consisting of surgical removal, temozolomide (TMZ) and radiotherapy fails to cure the disease and median survival is limited to 15 months. Therapeutic approaches targeting vascular endothelial growth factor (VEGF)-mediated angiogenesis, one of the majo...

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Detalles Bibliográficos
Autores principales: Urbantat, Ruth M., Jelgersma, Claudius, Vajkoczy, Peter, Brandenburg, Susan, Acker, Gueliz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350968/
https://www.ncbi.nlm.nih.gov/pubmed/35856448
http://dx.doi.org/10.3892/or.2022.8373