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Correlation of treatment outcome in sanger/RT-qPCR KIT/PDGFRA wild-type metastatic gastrointestinal stromal tumors with next-generation sequencing results: A single-center report

In patients with gastrointestinal stromal tumors (GIST), it has become mandatory to determine the driver mutation in order to predict the response to standard treatment with tyrosine kinase inhibitors (TKI). A total of 10–15% of all GIST lack activating mutations in KIT proto-oncogene, receptor tyro...

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Detalles Bibliográficos
Autores principales: Unk, Mojca, Bombač, Alenka, Jezeršek Novaković, Barbara, Stegel, Vida, šetrajčič Dragoš, Vita, Blatnik, Olga, Klančar, Gašper, Novaković, Srdjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351002/
https://www.ncbi.nlm.nih.gov/pubmed/35904169
http://dx.doi.org/10.3892/or.2022.8382