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Whole genome sequencing reveals the independent clonal origin of multifocal ileal neuroendocrine tumors

BACKGROUND: Small intestinal neuroendocrine tumors (SI-NETs) are the most common neoplasms of the small bowel. The majority of tumors are located in the distal ileum with a high incidence of multiple synchronous primary tumors. Even though up to 50% of SI-NET patients are diagnosed with multifocal d...

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Detalles Bibliográficos
Autores principales: Mäkinen, Netta, Zhou, Meng, Zhang, Zhouwei, Kasai, Yosuke, Perez, Elizabeth, Kim, Grace E., Thirlwell, Chrissie, Nakakura, Eric, Meyerson, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351068/
https://www.ncbi.nlm.nih.gov/pubmed/35922826
http://dx.doi.org/10.1186/s13073-022-01083-1