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Modeling early changes associated with cartilage trauma using human-cell-laden hydrogel cartilage models

BACKGROUND: Traumatic impacts to the articular joint surface are known to lead to cartilage degeneration, as in post-traumatic osteoarthritis (PTOA). Limited progress in the development of disease-modifying OA drugs (DMOADs) may be due to insufficient mechanistic understanding of human disease onset...

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Detalles Bibliográficos
Autores principales: He, Chunrong, Clark, Karen L., Tan, Jian, Zhou, Hecheng, Tuan, Rocky S., Lin, Hang, Wu, Song, Alexander, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351070/
https://www.ncbi.nlm.nih.gov/pubmed/35927702
http://dx.doi.org/10.1186/s13287-022-03022-8