Cargando…

The acidic tumor microenvironment enhances PD-L1 expression via activation of STAT3 in MDA-MB-231 breast cancer cells

Tumor acidosis, a common phenomenon in solid cancers such as breast cancer, is caused by the abnormal metabolism of cancer cells. The low pH affects cells surrounding the cancer, and tumor acidosis has been shown to inhibit the activity of immune cells. Despite many previous studies, the immune surv...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Yong-Jin, Seo, Eun-Bi, Jeong, Ae Jin, Lee, Song-Hee, Noh, Kum Hee, Lee, Sangsik, Cho, Chung-Hyun, Lee, Chang-Han, Shin, Hyun Mu, Kim, Hang-Rae, Moon, Hyeong-Gon, Ye, Sang-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351117/
https://www.ncbi.nlm.nih.gov/pubmed/35927628
http://dx.doi.org/10.1186/s12885-022-09956-9