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Irisin enhances chondrogenic differentiation of human mesenchymal stem cells via Rap1/PI3K/AKT axis

BACKGROUND: Human mesenchymal stem cells (hMSCs) have been proven to have inherent chondrogenic differentiation potential, which appears to be used in cartilage regeneration. Increasing evidence suggests that irisin enhances osteoblast differentiation of MSCs, but little is known about its potential...

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Detalles Bibliográficos
Autores principales: Chen, Taiqiu, Peng, Yan, Hu, Wenjun, Shi, Huihong, Li, Pengfei, Que, Yichen, Qiu, Jincheng, Qiu, Xianjian, Gao, Bo, Zhou, Hang, Chen, Yanbo, Zhu, Yuanxin, Li, Shaoguang, Liang, Anjing, Gao, Wenjie, Huang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351134/
https://www.ncbi.nlm.nih.gov/pubmed/35922833
http://dx.doi.org/10.1186/s13287-022-03092-8