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A deep learning framework for identifying essential proteins based on multiple biological information

BACKGROUND: Essential Proteins are demonstrated to exert vital functions on cellular processes and are indispensable for the survival and reproduction of the organism. Traditional centrality methods perform poorly on complex protein–protein interaction (PPI) networks. Machine learning approaches bas...

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Detalles Bibliográficos
Autores principales: Yue, Yi, Ye, Chen, Peng, Pei-Yun, Zhai, Hui-Xin, Ahmad, Iftikhar, Xia, Chuan, Wu, Yun-Zhi, Zhang, You-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351218/
https://www.ncbi.nlm.nih.gov/pubmed/35927611
http://dx.doi.org/10.1186/s12859-022-04868-8