SEMplMe: a tool for integrating DNA methylation effects in transcription factor binding affinity predictions

MOTIVATION: Aberrant DNA methylation in transcription factor binding sites has been shown to lead to anomalous gene regulation that is strongly associated with human disease. However, the majority of methylation-sensitive positions within transcription factor binding sites remain unknown. Here we in...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishizaki, Sierra S., Boyle, Alan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351228/
https://www.ncbi.nlm.nih.gov/pubmed/35927613
http://dx.doi.org/10.1186/s12859-022-04865-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351228/
https://www.ncbi.nlm.nih.gov/pubmed/35927613
http://dx.doi.org/10.1186/s12859-022-04865-x

Ejemplares similares