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SEMplMe: a tool for integrating DNA methylation effects in transcription factor binding affinity predictions
MOTIVATION: Aberrant DNA methylation in transcription factor binding sites has been shown to lead to anomalous gene regulation that is strongly associated with human disease. However, the majority of methylation-sensitive positions within transcription factor binding sites remain unknown. Here we in...
Autores principales: | Nishizaki, Sierra S., Boyle, Alan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351228/ https://www.ncbi.nlm.nih.gov/pubmed/35927613 http://dx.doi.org/10.1186/s12859-022-04865-x |
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