Salvianolic acid B activates chondrocytes autophagy and reduces chondrocyte apoptosis in obese mice via the KCNQ1OT1/miR-128-3p/SIRT1 signaling pathways

PURPOSE: Salvianolic acid B (Sal B) possesses strong anti-inflammatory and antioxidant activity. This study aims to explore the underlying mechanism of Sal B to improve the obesity-related osteoarthritis (OA). METHODS: C57BL/6 J male mice were fed with a normal control diet (NCD), a high fat diet (H...

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Detalles Bibliográficos
Autores principales: Sun, Tianwen, Wang, Fei, Hu, Gaojian, Li, Zhizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351265/
https://www.ncbi.nlm.nih.gov/pubmed/35922815
http://dx.doi.org/10.1186/s12986-022-00686-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351265/
https://www.ncbi.nlm.nih.gov/pubmed/35922815
http://dx.doi.org/10.1186/s12986-022-00686-0

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