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Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

BACKGROUND: One of the main difficulties of adoptive cell therapies with chimeric antigen receptor (CAR)-T cells in solid tumors is the identification of specific target antigens. The tumor microenvironment can present suitable antigens for CAR design, even though they are not expressed by the tumor...

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Detalles Bibliográficos
Autores principales: Martín-Otal, Celia, Lasarte-Cia, Aritz, Serrano, Diego, Casares, Noelia, Conde, Enrique, Navarro, Flor, Sánchez-Moreno, Inés, Gorraiz, Marta, Sarrión, Patricia, Calvo, Alfonso, De Andrea, Carlos E, Echeveste, José, Vilas, Amaia, Rodriguez-Madoz, Juan Roberto, San Miguel, Jesús, Prosper, Felipe, Hervas-Stubbs, Sandra, Lasarte, Juan Jose, Lozano, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351345/
https://www.ncbi.nlm.nih.gov/pubmed/35918123
http://dx.doi.org/10.1136/jitc-2021-004479