Adsorption free energy predicts amyloid protein nucleation rates

Primary nucleation is the fundamental event that initiates the conversion of proteins from their normal physiological forms into pathological amyloid aggregates associated with the onset and development of disorders including systemic amyloidosis, as well as the neurodegenerative conditions Alzheime...

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Detalles Bibliográficos
Autores principales: Toprakcioglu, Zenon, Kamada, Ayaka, Michaels, Thomas C. T., Xie, Mengqi, Krausser, Johannes, Wei, Jiapeng, Saric, Andela, Vendruscolo, Michele, Knowles, Tuomas P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351353/
https://www.ncbi.nlm.nih.gov/pubmed/35901206
http://dx.doi.org/10.1073/pnas.2109718119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351353/
https://www.ncbi.nlm.nih.gov/pubmed/35901206
http://dx.doi.org/10.1073/pnas.2109718119

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