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Adsorption free energy predicts amyloid protein nucleation rates
Primary nucleation is the fundamental event that initiates the conversion of proteins from their normal physiological forms into pathological amyloid aggregates associated with the onset and development of disorders including systemic amyloidosis, as well as the neurodegenerative conditions Alzheime...
Autores principales: | Toprakcioglu, Zenon, Kamada, Ayaka, Michaels, Thomas C. T., Xie, Mengqi, Krausser, Johannes, Wei, Jiapeng, Saric, Andela, Vendruscolo, Michele, Knowles, Tuomas P. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351353/ https://www.ncbi.nlm.nih.gov/pubmed/35901206 http://dx.doi.org/10.1073/pnas.2109718119 |
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